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The studies were evaluated based on participant selection, study group comparability, and the technique for identifying the association between e-cigarette exposure and COPD outcomes (Table S3)

Female participants were significantly more likely to agree (83.3%) compared to male (70.4%) participants ( 2 = 5.986, p = 0.05)

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Chronic obstructive pulmonary disease heterogeneity: challenges for health risk assessment, stratification and management

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